Aerobic and anaerobic soil degradation and metabolism studies using labelled and non-labelled substances (OECD 307) are conducted to elucidate the degradation rate of the applied parent substance as well as the formation and decline of possible metabolites.
Determination of soil adsorption constants with labelled and non-labelled substances (OECD 106) are carried out to predict the leaching behaviour of substances to groundwater. Assessment of the influence of time on the adsorption behaviour is used to simulate real environmental conditions. The HPLC method (OECD 121) is used to estimate the adsorption behaviour of a compound.
Metabolism studies in water/sediment systems under aerobic and anaerobic incubation conditions (OECD 308) are carried out to elucidate the environmental behaviour and metabolism of substances in aquatic systems. Water/sediment studies under artificial sunlight include direct and indirect photolytic processes.
Degradation/metabolism studies in surface water with and without sediment (OECD 309) are needed to get information about the behaviour, metabolism and mineralisation of substances in large bodies of water.
Hydrolysis studies with labelled and unlabelled substances (OECD 111) are carried out to assess the hydrolytic stability of substances and to elucidate abiotic degradation products. Direct and indirect photolysis studies in buffer or natural water (OECD 316) and on soil surface (OECD draft) are needed to assess the contribution of light during the degradation process.
Metabolism studies in sewer systems, activated sludge and anaerobic digester sludge (OECD 314 A, B and C) provide information about the degradation and metabolism behaviour of a chemical discharged in wastewater. Metabolism studies in liquid manure under anaerobic conditions (OECD draft) are performed to estimate environmental concentrations of veterinary products and biocides.
Residue studies from field trials on crops or with beneficial insects are carried out to generate information about residues in the respective compartments and to assess risks in the food chain. The results of field soil dissipation studies are used to assess the degradation/metabolism and leaching of agricultural substances under natural conditions.